After the graduation from the Conservatory of Music in Bratislava with the title „The Best Graduate of the Year“, Mirko Krajči continued his studies at the Academy of Music and Performing Arts in Bratislava. In 1992, he realized an internship in conducting at the Conservatoire National Superieur de Paris.

Since his studies until 1996, he cooperated with the Children and Youth Choir of the Slovak Radio as repetiteur, later as choirmaster. In 1996, he joined the Slovak Radio as dramaturgist and currently works as recording supervisor of the Slovak Radio. Since 1996, he has been the conductor and artistic director of the Technik Chamber Orchestra.

As conductor he collaborates intensively with the Slovak Radio Symphony Orchestra, as well as with numerous Slovak orchestras. He conducted in Austria, Czech Republic, England, France, Germany, Italy, Poland, Portugal. He collaborated with distinguished soloists: Julia Fischer, Ivan Zenaty, Vaclav Hudecek, Jan Talich, Jiri Barta, Zlata Chochieva, Miki Skuta and others.

Numerous of his compositions were commissioned by various orchestras and institutions: Bratislava Music Festival, Slovak National Theatre, Slovak Radio Symphony Orchestra, State Philharmony Kosice etc. For his music compositions, he has been awarded numerous prizes.